Register here The COBRE Center for Neuroplasticity at the University of Puerto Rico will co-sponsor the 10th Annual Meeting of the Puerto Rico Physiological Society, Saturday, October 22.

Oral and poster Presentation Awards for Undergraduates and Graduate Students

 Read More New NIH R21 grant at UPR School of Medicine!

The Department of Anatomy & Neurobiology and the Department of Microbiology of the School of Medicine of the Medical Sciences Campus of the University of Puerto Rico

 An interdisciplinary multi-campus center

Will implement improvements to the research infrastructure of Puerto Rico and will support a critical mass of investigators with shared scientific interests in the neurosciences.

Read More Read More INTEREST IN COBRE NEUROPLASTICITY CENTER NIEF FACILITIES, SEEDS AND PILOT RESEARCH PROJECTS

The NIH-NIGMS Centers of Biomedical Research Excellence (COBRE) Program seeks to augment and strengthen institutional biomedical research capabilities by expanding and developing biomedical faculty research through support of a multidisciplinary center.

Read More Island-wide Universities Open Call Collaborative Seeds Proposals (CCSP) Read More

The COBRE PHASE 2 Center for Neuroplasticity at the University of Puerto Rico aims to foster development of junior investigators into competitive researchers working on projects with broad biomedical significance

Read More

We Are COBRE

Centers of Biomedical Research Excellence augment and strengthen institutional biomedical research capabilities by expanding and developing biomedical faculty research capability through support of a multidisciplinary center led by a peer-reviewed, NIH-funded investigator with expertise central to the theme of the grant proposal.

MENTORED PROJECTS

Demetrio
Demetrio Sierra,

PhD

Came to the UPR Medical Sciences Campus from the Massachusetts General Hospital / Harvard University in 2014.

Personal blog / websiteE-mail
Jose
Jose Colón,

PhD

Alpha-7 nAChR: Potential Therapeutic Target for Obesity Induced Cognitive Decline

Personal blog / websiteE-mail
Alfredo
Alfredo Ghezzi,

PhD

Epigenetic control of transcription dynamics in long-term alcohol neuroadaptation

Personal blog / websiteE-mail
Amaya
Amaya Miquelajáuregui,

PhD

Role of microglial α7nAChR in diet induced brain inflammation.

Personal blog / websiteE-mail
Andrew
Andrew Seeds

Assistant Professor

Institute of Neurobiology, University of Puerto Rico, Medical Sciences Campus

Personal blog / websiteE-mail

Pilots Projects

Stefanie
Stefanie Hampel,

PhD

Establishing an experimental model for probing the neural and molecular basis of abnormally repetitive behavior

Personal blog / websiteE-mail
Bianca
Bianca Torres,

PhD

Polymorphism in neuroplasticity-related genes and its association with anxiety and depressive symptoms severity in Caribbean Hispanic patients

Personal blog / websiteE-mail
Jose
José E. Lizardi Ortiz

PhD

Role of Nicotinic Alpha 7 Autoreceptors in Striatal Cholinergic Interneurons

Personal blog / websiteE-mail
Steven
Steven Van Belleghem

PhD

Chromatin remodeling during butterfly brain development

Personal blog / websiteE-mail

Collaborative Seeds Projects

Dr. Nadezhda Sabeva

& Dr. Antonio H. Martins:

Ex vivo and in vivo models of Gulf War Illness Allow for Mechanistic Studies and the Search for Antidotes

& Dr. José Colón:

Synthesis of Biological Active Amino Derivatives and Multi-target Drugs for the Treatment of Alzheimer’s Disease

Dr. Priscila Sanabria

& Dr. Carlos Jiménez:

Xylazine effects on morphine-induced prefrontal cortex neuroplasticity

Dr. Yancy Ferrer

& Dr. Valance Washington:

Age-dependent involvement of inflammation associated receptors in hippocampal plasticity and neuroprotection after an ischemic insult

Dr. Luis Negrón

& Dr. José Rivera:

Lipid Dendrimer Nanoparticles for the Encapsulation of Brain-Derived Neurotrophic Factor and Simvastatin as a Non-Invasive Approach to Promote Neuroplasticity

Dr. Yancy Ferrer

& Dr. Antonio H. Martins:

Nuclear G-coupled Kinin-B2 Receptors in a Human hCMEC/D3 Blood Brain Barrier Cell title: Nuclear G-coupled B2 receptor

Request for Application or Funding Opportunities

PILOT PROJECT SUBMISSION

APPLY

SEED PROJECT SUBMISSION

APPLY

PILOT PROJECT SUBMISSION

APPLY

SEED PROJECT SUBMISSION

APPLY

SUBPROJECT SUBMISSION

APPLY

Research news

The COBRE UPR Center for Neuroplasticity celebrated its 10th Annual Retreat and Assessment Activity, May 25-26, 2023.

Left to right: John Ramírez, CoopSEI assessment team; Eduardo Nicolau, Interim Executive Director, Molecular Sciences Research Center; Jorge Miranda, COBRE NIEF Director; Irma Román-García, Assistant Director, UPR-MSC Deanship for Research; Jan-Marino Ramírez, COBRE EAC; Edjean Calderón, CoopSEI; José Lemos, COBRE EAC; Mark Miller, COBRE Administrative Core Director; José Lasalde, COBRE Program Director; Walter Silva, COBRE…

Details

New NIH R21 grant at UPR School of Medicine!

The Department of Anatomy & Neurobiology and the Department of Microbiology of the School of Medicine of the Medical Sciences Campus of the University of Puerto Rico are proud to announce that Associate Professors Dr. Demetrio Sierra Mercado and Dr. Filipa Godoy Vitorino, have been awarded an R21 research grant by the National Institutes of…

Details

Recents Publications

Group
Group1
Group2
Group3