Dr. Kevin De Leon and Dr. Bruno Marie recently published an article in the prestigious journal Genetics: “Autophagy, the ubiquitin proteasome system, and the MAPK pathway control the temperature dependence of synaptic growth”. Congratulations Dr. De Leon and Dr. Marie!

This study shows that developmental temperature does not affect all synapses equally. Using the Drosophila larval neuromuscular junction, we find that higher temperature selectively increases bouton number at phasic 1s motor terminals, while tonic 1b terminals remain stable. We identify neuronal autophagy and the Hiw-Wnd/P38b pathway as key regulators of this temperature-dependent structural remodeling. These…

Dr. Roberto Rodríguez Morales, COBRE II Pilot Project Leader, published an article in Animal Behaviour

Dr. Roberto Rodríguez Morales, COBRE II Pilot Project Leader, published an article in Animal Behaviour: Navarro-Pagan J, Figueroa-Colon P, Figueroa-Negron A, Perez-Fabregat L, Morales-Cintrón A, Mendoza-Anduce J, Ortiz-Franco A, Kozol RA, Rodriguez-Morales R. The resident effect dominates over previous winner/loser experience in surface fish of the Mexican tetra. Anim Behav. 2026 Aug;238:123636. doi: 10.1016/j.anbehav.2026.123636. Epub…

The COBRE Center for Neuroplasticity celebrated its 13th Annual Retreat and Assessment Activity

The program hosted the four members of its External Advisory Committee: Dr. Karen Echeverri (Marine Biological Lab, Woods Hole MA), Dr. Steven Treistman (UMass School of Medicine), Dr. José Lemos (UMass School of Medicine), and Dr. Jan Merino Ramírez (Seattle Children’s Hospital). UPR administrative personnel included Dr. Yasmin Pedrogo (Dean of Academic Affairs), Dr. Annabell…

Dr. José A. Lasalde, COBRE Center for Neuroplasticity Program Director, was awarded an EnTRUST Life Sciences Accelerator grant from the Puerto Rico Science Trust

Dr. José A. Lasalde, COBRE Center for Neuroplasticity Program Director, was awarded an EnTRUST Life Sciences Accelerator grant from the Puerto Rico Science Trust. Through the Technology Transfer Office, EnTRUST supports researchers across Puerto Rico in moving discoveries from the lab to real-world impact with mentorship, structure, and strategic guidance

COBRE Center for Neuroplasticity labs participated in an initiative aimed at strengthening Puerto Rico’s competitive capacity

The Puerto Rico Industrial Association announced the signing of a strategic agreement with the Molecular Sciences Research Center (MSRC) to structurally integrate advanced scientific research with local manufacturing operations. The initiative responds to the need to connect the island’s scientific infrastructure with its strong industrial base, enabling critical research and development processes, historically carried out in centers located in…

The COBRE Center for Neuroplasticity co-sponsored the 33rd Annual Puerto Rico Neuroscience Conference

Jaime Benítez Rexach Amphitheater, University of Puerto Rico Medical Sciences Campus. The conference was attended by over 400 students and faculty from institutions across the island. Dr. Yancy Ferrer (photo), COBRE Phase II Pilot Project leader, served as President of the Society and  Organizing Committee Chair. Keynote speakers included: Dr. Dhananjay “DJ” Bambah-Mukku, Assistant Professor…

The COBRE Center for Neuroplasticity co-sponsored a seminar presented by the group of Mark W. Miller, Director, COBRE Administrative Core.

The COBRE Center for Neuroplasticity co-sponsored a seminar presented by the group of Mark W. Miller, Director, COBRE Administrative Core.The seminar Neural Parasitology: Nervous System Structure and Function in an Intermediate Host for Schistosomiasis was held at the José del Castillo Conference Room at the UPR Molecular Sciences Research Center.