Dr. Kevin De Leon and Dr. Bruno Marie recently published an article in the prestigious journal Genetics: “Autophagy, the ubiquitin proteasome system, and the MAPK pathway control the temperature dependence of synaptic growth”. Congratulations Dr. De Leon and Dr. Marie!

This study shows that developmental temperature does not affect all synapses equally. Using the Drosophila larval neuromuscular junction, we find that higher temperature selectively increases bouton number at phasic 1s motor terminals, while tonic 1b terminals remain stable. We identify neuronal autophagy and the Hiw-Wnd/P38b pathway as key regulators of this temperature-dependent structural remodeling. These…

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Dr. Roberto Rodríguez Morales, COBRE II Pilot Project Leader, published an article in Animal Behaviour

Dr. Roberto Rodríguez Morales, COBRE II Pilot Project Leader, published an article in Animal Behaviour: Navarro-Pagan J, Figueroa-Colon P, Figueroa-Negron A, Perez-Fabregat L, Morales-Cintrón A, Mendoza-Anduce J, Ortiz-Franco A, Kozol RA, Rodriguez-Morales R. The resident effect dominates over previous winner/loser experience in surface fish of the Mexican tetra. Anim Behav. 2026 Aug;238:123636. doi: 10.1016/j.anbehav.2026.123636. Epub…

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Students from the Puerto Rico IDeA Network of Biomedical Research Excellence (PR-INBRE) Undergraduate Summer Internship Program (USIP) visited labs affiliated with the COBRE Center for Neuroplasticity.

Students from the Puerto Rico IDeA Network of Biomedical Research Excellence (PR-INBRE) Undergraduate Summer Internship Program (USIP) visited labs affiliated with the COBRE Center for Neuroplasticity. The students learned about neuroscience research conducted at the UPR Molecular Sciences Research Center.

Dr. Walter I Silva Ortíz, Center for Neuroplasticity Research Projects Core Director, participated in the 3rd External Advisory Committee Meeting of the COBRE Center for Promotion of Cancer Health Research (CePCHe)

Dr. Walter I Silva Ortíz, Center for Neuroplasticity Research Projects Core Director, participated in the 3rd External Advisory Committee Meeting of the COBRE Center for Promotion of Cancer Health Research (CePCHe).  Dr. Silva Ortíz directs the CePCHe Administrative Core.

COBRE Center for Neuroplasticity Research Projects Core Director, and Dr. Abel Baerga, COBRE Center for Promotion of Cancer Health Research Program Director, provided an orientation session on the newly implemented NIH and UPR Research Security Training (RST) and Domestic-only Research policies.

COBRE Center for Neuroplasticity Research Projects Core Director, and Dr. Abel Baerga, COBRE Center for Promotion of Cancer Health Research Program Director, provided an orientation session on the newly implemented NIH and UPR Research Security Training (RST) and Domestic-only Research policies. The session was shared with all UPR COBRE programs and participants.

The COBRE Center for Neuroplasticity celebrated its 13th Annual Retreat and Assessment Activity

The program hosted the four members of its External Advisory Committee: Dr. Karen Echeverri (Marine Biological Lab, Woods Hole MA), Dr. Steven Treistman (UMass School of Medicine), Dr. José Lemos (UMass School of Medicine), and Dr. Jan Merino Ramírez (Seattle Children’s Hospital). UPR administrative personnel included Dr. Yasmin Pedrogo (Dean of Academic Affairs), Dr. Annabell…

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A new publication from Dr. Luis Negrón and his group at UPR Cayey was featured on the morning news ! Dr. Negrón was supported by the COBRE Center for Neuroplasticity Phase II Collaborative Seeds Program.

A new publication from Dr. Luis Negrón and his group at UPR Cayey was featured on the morning news ! Dr. Negrón was supported by the COBRE Center for Neuroplasticity Phase II Collaborative Seeds Program. Negrón, L.M.; Camacho-Mercado, C.L.; Morales-Borges, C.A.; López-Colón, A.; De Jesús-Hernández, A.; Santiago-Figueroa, A.E.; Rodríguez-Rivera, J.M.; Ferrer-Acosta, Y.; Madera-Soto, B.A. Self-Assembly…

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Dr. José A. Lasalde, COBRE Center for Neuroplasticity Program Director, was awarded an EnTRUST Life Sciences Accelerator grant from the Puerto Rico Science Trust

Dr. José A. Lasalde, COBRE Center for Neuroplasticity Program Director, was awarded an EnTRUST Life Sciences Accelerator grant from the Puerto Rico Science Trust. Through the Technology Transfer Office, EnTRUST supports researchers across Puerto Rico in moving discoveries from the lab to real-world impact with mentorship, structure, and strategic guidance

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