Center for Neroplasticity at the University of Puerto Rico

The COBRE Center for Neuroplasticity at the University of Puerto Rico will co-sponsor the 10th Annual Meeting of the Puerto Rico Physiological Society, Saturday, October 22.

Oral and poster Presentation Awards for Undergraduates and Graduate Students

New NIH R21 grant at UPR School of Medicine!

The Department of Anatomy & Neurobiology and the Department of Microbiology of the School of Medicine of the Medical Sciences Campus of the University of Puerto Rico

An interdisciplinary multi-campus center

Will implement improvements to the research infrastructure of Puerto Rico and will support a critical mass of investigators with shared scientific interests in the neurosciences.

INTEREST IN COBRE NEUROPLASTICITY CENTER NIEF FACILITIES, SEEDS AND PILOT RESEARCH PROJECTS

The NIH-NIGMS Centers of Biomedical Research Excellence (COBRE) Program seeks to augment and strengthen institutional biomedical research capabilities by expanding and developing biomedical faculty research through support of a multidisciplinary center.

Island-wide Universities Open Call Collaborative Seeds Proposals (CCSP)

The COBRE PHASE 2 Center for Neuroplasticity at the University of Puerto Rico aims to foster development of junior investigators into competitive researchers working on projects with broad biomedical significance

We Are COBRE

Centers of Biomedical Research Excellence augment and strengthen institutional biomedical research capabilities by expanding and developing biomedical faculty research capability through support of a multidisciplinary center led by a peer-reviewed, NIH-funded investigator with expertise central to the theme of the grant proposal.

MENTORED PROJECTS

Demetrio Sierra,

PhD

Came to the UPR Medical Sciences Campus from the Massachusetts General Hospital / Harvard University in 2014.

Jose Colón,

PhD

Alpha-7 nAChR: Potential Therapeutic Target for Obesity Induced Cognitive Decline

Alfredo Ghezzi,

PhD

Epigenetic control of transcription dynamics in long-term alcohol neuroadaptation

Amaya Miquelajáuregui,

PhD

Role of microglial α7nAChR in diet induced brain inflammation.

Andrew Seeds

Assistant Professor

Institute of Neurobiology, University of Puerto Rico, Medical Sciences Campus

Pilots Projects

Stefanie Hampel,

PhD

Establishing an experimental model for probing the neural and molecular basis of abnormally repetitive behavior

Bianca Torres,

PhD

Polymorphism in neuroplasticity-related genes and its association with anxiety and depressive symptoms severity in Caribbean Hispanic patients

José E. Lizardi Ortiz

PhD

Role of Nicotinic Alpha 7 Autoreceptors in Striatal Cholinergic Interneurons

Steven Van Belleghem

PhD

Chromatin remodeling during butterfly brain development

Collaborative Seeds Projects

Dr. Nadezhda Sabeva

& Dr. Antonio H. Martins:

Ex vivo and in vivo models of Gulf War Illness Allow for Mechanistic Studies and the Search for Antidotes

& Dr. José Colón:

Synthesis of Biological Active Amino Derivatives and Multi-target Drugs for the Treatment of Alzheimer’s Disease

Dr. Priscila Sanabria

& Dr. Carlos Jiménez:

Xylazine effects on morphine-induced prefrontal cortex neuroplasticity

Dr. Yancy Ferrer

& Dr. Valance Washington:

Age-dependent involvement of inflammation associated receptors in hippocampal plasticity and neuroprotection after an ischemic insult

Dr. Luis Negrón

& Dr. José Rivera:

Lipid Dendrimer Nanoparticles for the Encapsulation of Brain-Derived Neurotrophic Factor and Simvastatin as a Non-Invasive Approach to Promote Neuroplasticity

Dr. Yancy Ferrer

& Dr. Antonio H. Martins:

Nuclear G-coupled Kinin-B2 Receptors in a Human hCMEC/D3 Blood Brain Barrier Cell title: Nuclear G-coupled B2 receptor

Request for Application or Funding Opportunities

Research news

Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila

May 7, 2024

The lab of Andrew Seeds and Stefanie Hampel published a new article in eLife: Link: https://elifesciences.org/articles/87602 “Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila”, Katharina Eichler, Stefanie Hampel, Adrián Alejandro-García, Steven A Calle-Schuler, Alexis Santana-Cruz, Lucia Kmecova, Jonathan M Blagburn, Eric D Hoopfer, and Andrew M Seeds. April 19, 2024.

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Neuroscience, Development and Physiology in a Changing Environment

May 7, 2024

Students, staff, and faculty from the UPR Center for Neuroplasticity took part in the symposium “Neuroscience, Development and Physiology in a Changing Environment”. The symposium assembled students and researchers from the University of Massachusetts, the Marine Biological Laboratory (Woods Hole, MA), and the University of Puerto Rico. It was co-sponsored by the NIGMS Centers of…

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